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Bipolar Disorder

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Mayo Clinic Psychiatrist Mark Frye, M.D., discusses how the work at the Mayo Clinic Depression Center is focused on providing a comprehensive diagnostic ...

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Mayo Clinic (Organization) Health Care (Issue) Healthcare Science (Field Of Study) Psychiatry Psychology Dr. Mark Frye Depression Individualized Treatment Pharmacogenomics Mayo Clinic Depression Center Mayo Clinic Center for Individualized Medicine Bipolar Risk Factors Mania Clinical Trial bipolar illness manic-depression manic-depressive disorder split personality alternating personality bipolar disorder dissociative identity dual personality multiple personality personality disorder Bipolar disorder Big Mad Bipolar Disorder Bi Polar Disorder oscillating undulating vacillating capricious inconstant mercurial spasmodic two-faced vibrating constant steady fixed reliable unmoving Bipolar Big Mad bipolar anarchy ataxia confusion derangement disarrangement disarray discombobulation disorderliness disorganization huddle irregularity jumble mess muddle shambles snarl untidiness topsyturviness method order organization rule system tidiness arrangement conformity health orderliness complication disturbance chaos unrest lawlessness trouble revolution agitation ruckus unruliness mayhem insurrection static rebellion convulsion flap misrule discord distemper fight hubbub strike clamor bustle turmoil tizzy fuss riot brawl imbroglio fracas entanglement turbulence tumult uproar hullabaloo rumpus dither quarrel terrorism anarchism reign of terror mob rule agreement harmony peace calmness quiet calm malady sickness disease affliction ailment complaint upset infirmity indisposition cachexia diseasedness unhealth happiness unsettle tumble embroil confuse confound clutter disjoint shuffle discompose derange dishevel disrupt rummage disorganize disturb rumple dislocate scatter mess up discreate muss up conform arrange clear up clarify compose systematize regulate comfort soothe tidy neaten organize explain enlighten adversity anguish calamity cross crux depression difficulty disorder distress grief hardship illness misery misfortune ordeal pain plague plight scourge sorrow suffering torment trial tribulation woe help good fortune blessing benefit pleasure cheer well-being good health relief consolation aid encouragement contentment good luck delight boon profit advantage joy ache bug condition dose flu syndrome ailments disregard hostility nihilism nongovernment lawfulness ball up destroy make unclear mix up ruin scramble balled up Disorder Big Mad mayo Big Mad Mayo hospital dispensary infirmary sick bay surgery center faculties academics advisers body clinic college corps department employees institute literati mentors organization personnel professorate profs researchers scholars society staff university workers students need ineptness lack incompetence inability faculty hospice asylum emergency room health service institution nursing home rest home sanatorium sanitarium shelter surgery ward hospitals academy association business company conservatory establishment fixture foundation guild orphanage school seminar seminary system think tank Big Mad Clinic energy fitness strength well-being bloom complexion constitution euphoria fettle form haleness hardihood hardiness healthfulness healthiness lustiness pink prime robustness salubriousness salubrity shape soundness stamina state tone tonicity verdure vigor wholeness clean bill eupepsia fine feather good condition top form lethargy weakness disease illness infirmity sickness condition appearance aspect build health kilter mint order phase repair status trim bliss dreamland ecstasy elation exaltation exhilaration exultation frenzy glee high spirits intoxication joy joyousness jubilation madness rapture relaxation transport misery depression discouragement unhappiness woe despair dislike sorrow sadness good health poor health unsuitability inappropriateness enervation anatomy being figure frame object outline person phenomenon physique silhouette thing torso disorganization disarrangement forms luck advantage big break blessing break fluke fortunateness godsend good luck happiness in the cards karma kismet luckiness lucky break occasion opportunity profit prosperity run of luck serendipity smile streak of luck stroke success triumph victory weal wealth win windfall bad fortune failure misfortune disadvantage bad luck poverty loss forfeit Health HEALTH responsibility affliction aggravation alarm anguish annoyance anxiety apprehension bother burden chagrin charge consternation discomposure dismay disquiet distress disturbance encumbrance exasperation fear foreboding fretfulness handicap hardship hindrance impediment incubus load misgiving nuisance onus oppression perplexity pressure solicitude sorrow stew strain stress sweat tribulation trouble uneasiness unhappiness vexation woe worry advantage aid assistance assurance benefit blessing calm calmness comfort composure confidence contentment delight ease encouragement happiness health help joy joyfulness peace peacefulness pleasure relief tranquility carelessness disregard ignorance inattention neglect negligence omission oversight thoughtlessness management effort wariness fastidiousness caution concentration watchfulness particularity concern circumspection meticulousness discrimination nicety scrupulousness interest vigilance exactness alertness exertion direction diligence regard prudence forethought conscientiousness enthusiasm consideration thought heed precaution pains disinterest disrespect lethargy laziness apathy indifference indiscretion imprudence heedlessness control trust protection supervision safekeeping administration keeping superintendence aegis ward auspices tutelage guardianship ministration wardship watch tend protect consider attend sit treasure mind foster minister mother nurse nurture ride herd on wait on pay attention to baby sit keep an eye on keep tabs on look after mind the store provide for take pains watch over forget hurt hate dislike injure ignore enjoy love want cherish desire respect like prize be crazy about be fond of find congenial hold dear take to despise affection amore ardor attachment care case closeness crush devotion emotion endearment feeling friendliness friendship good will hankering heart inclination itch kindness liking passion predilection propensity puppy love sentiment shine soft spot tenderness warmth weakness yen ill will enmity animosity antipathy coldness hatred advancement advice advocacy alleviation allowance assist attention backing backup benefaction benevolence bounty charity compensation cooperation deliverance endowment favor furtherance gift giving guidance hand handout leg up lift ministry patronage promotion reinforcement rescue reward salvation service shot in the arm subsidy sustenance treatment unkindness malevolence stop taking opposition obstruction blockage silence disfavor harm stoppage injury damage penalty loss all-overs angst ants in pants botheration butterflies cold sweat creeps disquietude doubt downer drag dread flap fuss goose bumps heebie-jeebies jitters misery mistrust nail-biting needles nervousness panic pins and needles restlessness suffering suspense uncertainty unease willies worriment faith belief sureness security certainty nonchalance collectedness assiduity assiduousness attentiveness doggedness industriousness industry persistence sedulousness indolence idleness attention(s) amenity civility compliment deference gallantry mindfulness politeness Care Health care Big Mad Healthcare Health Care art discipline education information learning skill system technique branch erudition lore scholarship wisdom body of knowledge disorder disorganization ignorance culture ability accomplishment address aestheticism capacity civilization class courtesy cultivation delicacy dignity discrimination dress elegance elevation enlightenment experience fashion finish gentility good taste grace improvement kindness manners nobility perception polish politeness practice proficiency refinement savoir-faire science tact training urbanity ineptness tactlessness rudeness impoliteness inelegance roughness crudeness bad manners clumsiness hurt harm incompetence coarseness inexperience inability cultures apprenticeship background book learning brainwashing breeding catechism coaching direction drilling edification guidance inculcation indoctrination learnedness literacy nurture pedagogy preparation propagandism proselytism reading rearing schooling study teaching tuition tutelage tutoring neglect destruction bookishness brains intellectuality knowledge letters pedantry savvy scholarliness studiousness advice ammo break chapter and verse clue confidence counsel cue data dirt dope dossier earful illumination info inside story instruction intelligence leak lowdown material message network notice notification orientation propaganda report scoop score tidings tip whole story word question silence accomplishments acquaintance apprehension awareness cognition comprehension consciousness discernment doctrine dogma expertise facts familiarity goods grasp insight judgment know-how light observation philosophy picture power principles recognition substance theory misunderstanding stupidity impotence unbelief weakness inanity SCIENCE! Science psychiatry Big Mad Psychiatry attitude medicine therapy behaviorism mental make-up mental processes personality study psych science of the mind way of thinking where head is at ethos beliefs code culture habits ideology mentality mind mindset principles psyche psychology spirit traits values body physicality ethoses brainpower brains cast character comprehension disposition frame of mind headset intellect intelligence quotient makeup mental age outlook personality rationality reasoning routine sense turn of mind understanding wit disbelief Psychology Big Mad Big Mad D.R. Dr. impression imprint line point record scar score signature spot stain stamp streak symbol autograph blaze blot blotch brand bruise check cross dent dot ink label logo nick pock register representation scratch sign smudge splotch stroke tag ticket trace trademark underlining John Hancock John Henry brand name blank clarity unimportance marking hallmark attribute image evidence peculiarity seal quality particularity index character feature note print type emblem trait virtue device earmark incision badge token indication idiosyncrasy distinction property affection proof significant indicia level yardstick gauge norm measure function duty use end object aim prey purpose ambition objective result value effect standing dignity notice regard influence notability manifestation consequence eminence prestige fame neglect cause insignificance inferiority ignorance heedlessness lowliness source impress underline pinpoint initial write inscribe letter chalk lose smooth mend signify show indicate identify demonstrate illustrate evince exemplify remark exhibit individualize proclaim singularize betoken bespeak qualify manifest distinguish signalize denote designate check off point out show up individuate mark off ostend point up set apart stake out cover confuse hide conceal observe attend eye chronicle watch mind perceive hearken behold discern view pay attention pay heed take notice of write down overlook look away disbelieve disregard ignore endorsement inscription mark undersignature address consign dispatch forward postmark remit route send ship superscribe transmit pass receive retain keep hold slight shun cut avoid addressed addresses addressing aspiration course desideratum design desire direction intent intention plan scheme target where one is heading wish thoughtlessness avoidance hatred hate dislike Mark Big Mad Frye Big Mad abasement abjection blahs bleakness bummer cheerlessness dejection desolation desperation despondency discouragement dispiritedness distress dole dolefulness dolor downheartedness dreariness dullness dumps ennui gloom gloominess heavyheartedness hopelessness lowness melancholia melancholy misery mortification qualm sadness sorrow trouble unhappiness woefulness worry abjectness blue funk disconsolation heaviness of heart lugubriosity the blues advantage benefit blessing cheer comfort contentedness contentment encouragement gladness happiness hopefulness joy liveliness peace pleasure bulge cheerfulness convexity hope protuberance recovery surge drop sag dislocation crisis bankruptcy bust downturn panic stagnation crash slump failure inflation inactivity recession slide slowness unemployment stagflation overproduction deflation retrenchment paralysis bear market big trouble bottom out hard times rise success calm increase impression bowl vacuity dimple dent excavation crater pit vacuum hollow pocket scoop void sink indentation sinkhole hole valley dip basin sinkage solid fullness mountain affliction adversity anguish calamity cross crux depression difficulty disease disorder grief hardship illness infirmity misfortune ordeal pain plague plight scourge sickness suffering torment trial tribulation woe help good fortune well-being good health relief consolation aid good luck delight boon profit health angst Weltschmerz agony apprehension blues dread mid-life crisis misgiving nervousness uneasiness confidence calmness baby blue eyes low spirits peepers postpartum depression baby blues bay concavity ewer gulf lagoon pan pool pot tub vessel washbasin washbowl watershed funk Depression Big Mad analyze ascertain categorize characterize classify collate decide demarcate determine diagnose differentiate discriminate divide estimate extricate finger identify individuate judge know label mark name part pinpoint place qualify recognize select separate sift signalize singularize specify spot tag determinate diagnosticate figure out make out mark off set apart set off single out sort out tell apart tell between tell from allow combine confuse connect disarrange forget hesitate ignore join link lose miss misunderstand mix up overlook unite detailed abundant accurate all-inclusive amplified at length blow-by-blow circumstantial circumstantiated clocklike complete complicated comprehensive copious definite described developed disclosed elaborate elaborated enumerated exact exhausting exhaustive finicky full fussy individual individualized intricate meticulous minute narrow nice point-by-point precise seriatim specific specified thorough undetailed nonspecific brief simple careless imprecise false uncomplicated sparing cursory needy incomplete vague uncertain indefinite questionable inexact inaccurate more detailed analysis cure hospitalization medication medicine operation prescription regimen remedy surgery therapy diet healing therapeutics disease injury harm hurt management employment practice strategy conduct approach method procedure proceeding reception habit custom manner way manipulation usage angle line execution mode modus operandi dealing processing action towards behavior towards aid advancement advice advocacy alleviation allowance assist assistance attention backing backup benefaction benefit benevolence bounty care charity comfort compensation cooperation deliverance encouragement endowment favor furtherance gift giving guidance hand handout leg up lift ministration ministry patronage promotion reinforcement relief rescue reward salvation service shot in the arm subsidy sustenance treatment unkindness malevolence stop taking opposition handicap obstruction impediment blockage ill will silence disfavor stoppage hindrance damage penalty loss application administering administration applying creaming dosing rubbing applications TLC awareness big rush brace concern consciousness looking after notice observation recognition regard spotlight tender loving care neglect negligence disregard heedlessness ignorance carrying on channels charge control direction handling intendance leadership organization oversight plan policy posture red tape regulation rule running superintendence supervision tactics transaction wielding mismanagement disorganization antidote catholicon corrective counteractant counteragent countermeasure drug elixir elixir vitae fix healing agent help medicament medicant nostrum panacea pharmacon physic placebo proprietary quick fix recovery redress reparation restora-tive therapeutic problem Big Mad inside interior intermediary intermediate mean midpoint midway at halfway point centermost deepest equidistant inmost inner innermost internal medial mid middlemost exterior external extreme outer outside bordering edging marginal peripheral heart place hub kernel essence focus seat pivot midst axis core gist nucleus marrow mainstream pith quick root focal point middle of the road nave omphalos polestar centrality hotbed cynosure centrum navel centriole equidistance intermediacy radial point edge border exteriority surroundings rim periphery outskirts margin boundary town city shopping center plaza club mall station capital market marketplace metropolis mart concourse crossroads meeting place nerve center social center trading center meet attract gather intensify consolidate centralize unify collect join concenter focalize bring to a focus bring together close on converge upon medialize dissipate separate divide scatter disperse disjoin armory arsenal center depot dump factory headquarters magazine plant range base camp dock field garrison hangar harbor home port post settlement site starting point strip terminal branch top annex basis antecedent assumption authority axiom backbone background backing bedrock cause chief ingredient crux data dictum essential evidence explanation footing fundamental hard fact infrastructure justification keynote keystone law nexus postulate premise presumption presupposition principal element principle proof reason rudiment sanction security source substratum support theorem theory underpinning warrant end effect fact result surface trivia auxiliary reality bosom circle conscience emotions feelings sentiments soul spirit sympathies bull's-eye butt dead center direct hit hole in one home run quintain target capitol Capitol Hill dome legislative hall political scene seat of government statehouse Center as long as because being considering inasmuch as now since whereas after concerning during notwithstanding pro supposing toward beneficial to conducive to for the sake of in contemplation of in exchange for in favor of in furtherance of in order to in order to get in place of in pursuance of in spite of in the direction of in the interest of in the name of on the part of on the side of to counterbalance to go to to the amount of to the extent of under the authority of with a view to with regard to with respect cause for for the reason that seeing that as a result of as things go by cause of by reason of by virtue of due to in as much as in behalf of in that in view of now that on the grounds that over owing to seeing thanks to through behind backing in agreement supporting all in all all things considered everything being equal forasmuch as in consideration of in light of insomuch as pending taking into account favor accept advocate appreciate approbate approve back be in favor of buck for champion choose commend cotton to countenance encourage endorse esteem eulogize fancy flash on go for hold with honor incline lean toward look up to opt for patronize pick praise prize regard highly root for sanction single out support take a liking to take a shine to take to think well of tilt toward value disfavor hurt disrespect disagree discourage criticize neglect oppose thwart hinder deny hate dislike censure disallow dissuade protest disapprove reject refuse favoring Big Mad FOR For antibiotic cure drug medication pharmaceutical pill prescription remedy anesthetic antidote antiseptic antitoxin balm capsule dose elixir injection inoculation liniment lotion medicament ointment physic potion salve sedative serum tablet tincture tonic vaccination vaccine biologic pharmacon disease anatomy analysis biology cytology diagnosis dissection division embryology etiology examination genetics histology inquiry investigation medicine morphology physiology zoology connection antivenin corrective counteractant counteragent countermeasure counterstep negator neutralizer nullifier preventive antibody antipoison antiserum analgesic application balsam cerate compound cream demulcent dressing embrocation emollient formula poultice preparation soother soothing agent unction unguent counteractive aid alleviation assistance catholicon elixir vitae fix healing healing agent help medicant nostrum panacea placebo proprietary quick fix recovery redress reparation restora-tive therapeutic treatment problem stop obstruction hurt hindrance blockage injury Big Mad Medicine danger exposure hazard liability opportunity peril possibility prospect uncertainty accident contingency flyer fortuity fortune gamble header jeopardy luck openness plunge speculation stab venture wager exposedness liableness shot in the dark certainty safety security misfortune plan protection reality truth sureness surety endanger imperil jeopardize compromise defy speculate brave confront encounter face chance adventure tackle meet menace dare beard take on be caught short defy danger expose to danger hang by a thread leap before looking leave to luck play with fire put in jeopardy run the chance run the risk skate on thin ice take a flyer take a header take a plunge take the liberty be careful design run away neglect save retreat avoid hide dodge protect guard awkwardness bulkiness chanciness cumbersomeness hazardousness inconvenience perilousness risk troublesomeness uncomfortableness unhandiness unmanageability unwieldiness straightforwardness ease convenience handiness grace cleverness easiness skill elegance dexterity artfulness bet ante buy in on dice game lay down lay odds play against play for play the ponies pledge pony up put put money on set tempt fortune toss up trust remove displace action betting down on long shot lot lottery odds odds on parlay play pot raffle random shot shot stake sweepstakes bite be victim get hooked nibble volunteer bear challenge court face off fly in the face of go through outdare stand up to suffer support withstand skip give up break down yield fear complain capitulate reject refuse surrender Risk Big Mad RISK aspect cause circumstance component consideration element influence ingredient part point thing agency agent aid antecedent board constituent instrument instrumentality item means portion part and parcel whole factor Big Mad Factor factors craving craze craziness dementia enthusiasm fad fascination frenzy infatuation lunacy obsession passion rage aberration bee bug compulsion delirium derangement desire disorder fancy fetish furor grabber hang-up insanity monomania partiality preoccupation thing tiger ax to grind bee in bonnet bug in ear fixed idea idée fixe on the brain tiger by the tail calmness dislike hate indifference balance conformity hatred soundness mania zeal lethargy apathy bugs complex a thing about something anxiety exaggerated reaction fear fixation neurosis phobia repression sanity complexes chic cry fashion fever in thing kick mode newest wrinkle novelty the last word the latest thing trend vogue wrinkle calm coldness ardor ecstasy fervor fury hallucination hysteria raving transport peace saneness coolness happiness Big Mad Mania analytic impersonal scientific antiseptic cold detached disinterested emotionless objective unemotional feeling passionate subjective neutral aloof bystanding calm clinical collected cool disengaged dispassionate easy evenhanded fair-minded inactive indifferent inert middle-of-road nonaligned nonbelligerent nonchalant noncombatant nonparticipating nonpartisan on sidelines on the fence pacifistic poker-faced relaxed unaligned unbiased uncommitted unconcerned undecided uninvolved unprejudiced strong loud bright partial committal decided prejudiced involved concerned predisposed agitated excited interested biased impartial neuter caring active working Big Mad Clinical exploratory preliminary balloon pilot test testing probationary provisional tentative definite known proven experiment investigation examination struggle probation effort essay lick shot shakedown hassle experience endeavor check experimentation crack whack assay fling workout audition stab attempt undertaking analysis try venture tryout proof dry run trial and error trial run try on showcase striving research and development test run peace happiness abstention laziness idleness case litigation tribunal suit prosecution hearing contest arraignment action indictment lawsuit claim citation seizure rap impeachment counterclaim cross-examination court action court martial habeas corpus acquittal ordeal load distress affliction irritation anguish unhappiness blow annoyance misfortune nightmare heartbreak tribulation woe vicissitude wretchedness sorrow pain hardship crucible visitation inconvenience complication bane difficulty suffering plague burden nuisance care grief albatross bother drag pest misery rigor vexation thorn adversity pain in the neck calvary cross to bear hard time severe test trying time fortune convenience ease cheer good fortune joyousness felicity help pleasure comfort blessing benefit good luck profit favor calm delight joyfulness joy contentment relief aid advantage health acid test conclusive test crucial test decisive test definitive test genuineness proving ground substantiation sure test test of value trial verification adversities bad break bummer calamity can of worms catastrophe clutch contretemps crunch disaster downer evil eye hard knocks hard times hurting ill fortune jam jinx kiss of death mishap on the skids poison reverse the worst tough luck trouble wonder prosperity encouragement boon assistance success miracle cross crux depression disease disorder illness infirmity plight scourge sickness torment well-being good health consolation bill of indictment charge denunciation summons appraisal assessment estimation evaluation inspection measurement rating survey valuation neglect ignorance Trials Big Mad
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