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Exercise in pill: Yoda1 molecule can activate Piezo1 protein, the body's exercise sensor - TomoNews

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LEEDS, UNITED KINGDOM — Researchers at the University of Leeds are exploring activating the body's exercise sensor with a molecule named Yoda1.During physical activity, the heart pumps more blood around the body, putting more pressure on the walls of the blood vessels.According to the study, the Piezo1 protein in the endothelium, which takes blood from the heart to stomach and intestines, senses the change and becomes activated, which constricts the blood vessels. As a result, more blood is directed to the brain and the muscles involved in the physical activity."We know that exercise can protect against heart disease, stroke and many other conditions. This study has identified a physiological system that senses when the mammalian body is exercising," Professor David Beech, from the Leeds Institute of Cardiovascular and Metabolic Medicine and lead investigator of the study told Eurekalert.Based on experiments on mice, the team discovered an experimental molecule named Yoda1 can increase the blood flow in the endothelium similar to the effect of exercise and thus can activate Piezo1 protein without undergoing exercise. Researchers believe the same results could happen on human bodies.The study was published in the journal Nature Communications.----------------------------------------­---------------------Go to https://www.patreon.com/tomonews and become a Patron now TomoNews is now on Patreon and we've got some cool perks for our hardcore fans.TomoNews is your best source for real news. We cover the funniest, craziest and most talked-about stories on the internet. Our tone is irreverent and unapologetic. If you’re laughing, we’re laughing. If you’re outraged, we’re outraged. We tell it like it is. And because we can animate stories, TomoNews brings you news like you’ve never seen before.Visit our official website for all the latest, uncensored videos: http://us.tomonews.com Check out our Android app: http://bit.ly/1rddhCj Check out our iOS app: http://bit.ly/1gO3z1f Get top stories delivered to your inbox everyday: http://bit.ly/tomo-newsletter See a story that should be animated? Tell us about it! Suggest a story here: http://bit.ly/suggest-tomonews Stay connected with us here:Facebook http://www.facebook.com/TomoNewsUS Twitter @tomonewsus http://www.twitter.com/TomoNewsUS Google+ http://plus.google.com/+TomoNewsUS/ Instagram @tomonewsus http://instagram.com/tomonewsus

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