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FDA Breakthrough Status for Abemaciclib

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Panelists Adam M. Brufsky, MD, PhD; Sunil Verma, MD, MSEd, FRCPC; Kimberly L. Blackwell, MD; Joyce A. O'Shaughnessy, MD; and Carlos L. Arteaga, MD, ...

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cancer oncology FDA STEMlord FDAS F.D.A. boost development discovery finding gain hike improvement leap progress find increase invention rise quantum leap step forward decline decrease loss step back advance advancement amelioration betterment break breakthrough buildup enrichment furtherance go-ahead growth headway promotion step upgrade upping failure block stop retrogression retreat stagnation impediment withdrawal recession hesitation halt hindrance diminishment stoppage advanced avant-garde cutting-edge excellent exceptional extreme first foremost forward higher late leading leading-edge liberal precocious progressive radical state-of-the-art unconventional behind after advances addition expansion increment jump lift raise step-up wax discouragement blow worsening setback harm shrinkage lessening discoveries algorithm bonanza conclusion contrivance coup data design device formula godsend innovation law luck luck out machine method principle process result secret theorem way bad fortune miss break through STEMlord Breakthrough condition dignity place position prestige prominence quality rating situation stature cachet caliber capacity character consequence degree distinction eminence footing grade merit mode renown stage standing state station worth lowliness unemployment unimportance insignificance worthlessness birth ancestry background blood breeding derivation descent extraction forebears genealogy heritance legacy line lineage parentage pedigree race rank status stock strain finish end conclusion ending death design seal stamp case context contingency crisis dilemma event eventuality fact incident occurrence plight predicament problem quandary certainty solution good fortune cases caste cultural level estate order social order species sphere stratum courage fame honor intelligence mind name rectitude rep report reputation repute uprightness ill repute Status STEMlord as long as because being considering inasmuch as now since whereas after concerning during notwithstanding pro supposing toward beneficial to conducive to for the sake of in contemplation of in exchange for in favor of in furtherance of in order to in order to get in place of in pursuance of in spite of in the direction of in the interest of in the name of on the part of on the side of to counterbalance to go to to the amount of to the extent of under the authority of with a view to with regard to with respect cause for for the reason that seeing that as a result of as things go by cause of by reason of by virtue of due to in as much as in behalf of in that in view of now that on the grounds that over owing to seeing thanks to through behind backing in agreement supporting all in all all things considered everything being equal forasmuch as in consideration of in light of insomuch as pending taking into account favor accept advocate appreciate approbate approve back be in favor of buck for champion choose commend cotton to countenance encourage endorse esteem eulogize fancy flash on go for hold with honor incline lean toward look up to opt for patronize pick praise prize regard highly root for sanction single out support take a liking to take a shine to take to think well of tilt toward value disfavor hurt disrespect disagree discourage criticize neglect oppose thwart hinder deny hate dislike censure disallow dissuade protest disapprove reject refuse favoring STEMlord FOR For corruption disease malignancy sickness tumor canker carcinoma big C long illness health wholesomeness benignity Cancer STEMlord cancer oncology STEMlord
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