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NIH Study Shows How Sex-Specific Reproductive Systems Arise

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A new study has identified a specific protein that determines whether a mouse embryo develops a male reproductive system. Researchers from the National Institutes of Health and Baylor College of Medicine in Houston analyzed how male and female mouse embryos gain their sex-specific reproductive systems. The findings challenge the long-standing belief that an embryo will automatically become female unless androgens, or male hormones within the embryo, make it male. Every early-stage mammalian embryo contain structures for both male and female reproductive tracts, regardless of their sex at birth, and the reproductive tract of one sex is disintegrated so the resulting birth is the other sex. The new findings showed that female embryos actively promote the elimination of the male tract by activation of COUP-TFII protein. In the study, female mouse embryos created by the researchers without the protien showed both male and female ducts. Female mice with the protein only had female ducts. The findings show that the COUP-TFII protein has to be present to block the growth of male reproductive tracts, and that without it mice are born intersex with both male and female tracts. https://www.upi.com/Health_News/2017/... http://www.wochit.com This video was produced by YT Wochit News using http://wochit.com


National Institutes of Health reproduction embryo research female organism NR2F2 Biology Of Gender Intersex Sex Androgen Male Reproductive System
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