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New diagnostic sensors: for the analysis of expired human breathing to diagnose diseases.

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New diagnostic sensors: for the analysis of expired human breathing to diagnose diseases.A research group led by Prof. Il-Doo Kim in the Department of Materials Science has produced diagnostic sensors using protein encapsulated nanocatalysts, which could aid in the diagnosis of specific diseases by examining human exhaled respiration. This new technology allows the early monitoring of different diseases through the recognition of gas patterns biomarkers associated with diseases in human exhalation.The protein matrix catalyst synthesis pathway is extremely simple and versatile to develop only one component of catalytic nanoparticles and also various heterogeneous intermetallic catalysts that are less than 3 nm. Researchers have developed chemotherapeutic sensors that are much more sensitive and selective and that are capable of potentially diagnosing particular diseases by the analysis of exhaled respiratory gases. The results of this study, which were contributed by Dr. Sang-Joon Kim and Dr. Seon-Jin Choi as First Authors, were chosen as the article covered in the July issue of Chemical Research Accounts. In human respiration, various components are detected, including hydrogen, water vapor, acetone, toluene, ammonia, carbon monoxide and hydrogen sulfide, which are exhaled more and more from patients. Some of these components are associated with diseases such as halitosis, diabetes mellitus type 1, lung cancer and asthma.

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