Possibility of treatment with transfer of nano tissue to live skin cellResearchers have developed a device that changes the function of cells by delivering new DNA or RNA in less than a minute to living skin cells.Scientists in the United States have developed a new technology called Tissue Nanotransfection (TNT) that can alter the function of cells by transcribing new DNA or RNA into living skin cells in less than a minute. With the technology that allowed the artificial production of cell types needed in the patient's body, the damaged tissues of mice and pigs were treated shortly.Developed by researchers from the Ohio State University Wexner Medical Center and the Ohio State University Engineering Faculty, TNT consists of a nanotechnology chip that will carry a special biological cargo containing new DNA and RNA designed for cell transformation and carry it to adult living cells.Researchers Daniel Gallego-Perez said that when this biological cargo was transferred to adult living cells using nanochip, it turned the cell into a cell of another species. Perez pointed out that TNT can be applied even in the tests on the patient's side without the need for laboratory procedures, stressing that the biological carcass was delivered with a little energy that even the patient could not feel.Researchers who have succeeded in transforming skin cells into muscle cells in experiments carried out on mice and pigs have injected these cells into injured and non-blood-flowy legs. Within one week the blood cells of the legs appeared and in the second week the bug was fully cured.On the other hand, it was observed that when the skin cells that turned into nerve cells were brain damaged and injected into the mouse, which remained paralyzed, the pharynx could move again.The research's lead writer is the director of Ohio State Center for Regenerative Medicine and Cell-Focused Therapies. Chandan Sen said that the dream of the technology they developed was difficult but unattainable.You said, "98 percent of the work we have done is successful, and it's very easy to implement on the patient, and the chip does not stay in your body." With the technology we developed, the cells are being reprogrammed under the supervision of the immune system, without the need to suppress the immune system.Sen, who added that the procedure could even be performed during outpatient treatment, said that they were even surprised that TNT worked so well. "We proved to be a highly productive environment in which we can regenerate the cells of any organ that is deeply weakened." Used expressions.You, TNT, will start testing people on next year.The results of the study were published in Nature Nanotechnology.
TagsPossibility of treatment with transfer of nano tissue to live skin cell Researchers Daniel Gallego-Perez said that when this biological cargo was transferred to adult living cells using nanochip it turned the cell into a cell of another species Perez pointed out that TNT can be applied even in the tests on the patient's side without the need for laboratory procedures stressing that the biological carcass was delivered with a little energy that even the patient could not feel.