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Repatha: The cholesterol-shedding drug can protect high-risk heart patients.

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Repatha: The cholesterol-shedding drug can protect high-risk heart patients.The first rigorous trial of a new expensive drug that radically reduces cholesterol levels found that significantly reduces the likelihood that a high-risk patient would have a heart attack or stroke. These were men and women who had exhausted all other options. The results, which cost about $ 1 billion and were paid by Amgen, the drug's maker, were published Friday in The New England Journal of Medicine and presented at the annual meeting of the American College of Cardiology.The drug, Repatha, is called a PCSK9 inhibitor and can make cholesterol fall to levels almost never seen naturally in adults, and even in people taking statins to lower cholesterol. Amgen and a similar drug, marketed by Sanofi and Regeneron, were approved by the Food and Drug Administration in 2015 with hope - and expectation - that they would reduce the risk of heart attacks and strokes, and not only reduce LDL cholesterol levels, the dangerous type.This is like the era of statin coming, Dr. Eugene Braunwald, a cardiologist at Harvard Medical School, who did not participate in the study. Like statins, which were introduced in the 1980s, the new class of medications has the potential to improve the health and longevity of millions of Americans with heart disease, the leading cause of death in the country, representing One in four deaths.But the cost will be a problem. Statins are available as cheap generics. New drugs have a list price of $ 14,523 a year. The next big challenge is financial: how to pay for it, insurance companies have been reluctant to pay for the drug without evidence that protected high-risk patients from heart attacks and strokes. Kristine Grow, a spokeswoman for the organization of insurers Health Insurance Plans United States.#Repatha #PCSK9Inhibitor #Drug #HighCholesterol #Risk #HeartAttack #Stroke #Organization #LDL #Cholesterol #Generics #Insurance #Cerebrovascular #HeartAttacks #Statins #Health #Medication #Cardiology


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