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Understanding MRD Testing in CLL

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Thomas J. Kipps, MD, PhD, reviews the advantages and disadvantages of the different MRD testing platforms in terms of their accuracy, sensitivity, and standardization in patients with chronic lymphocytic leukemia, as well as what the future looks like for the field.


cancer oncology kindly kind patient selfish mean sense grasp grip wit acumen ken reason savvy ignorance disbelief mistake stupidity idea meaning opinion view purport inkling import message notion pact accord harmony deal concord aptitude capability capacity competence competency comprehension dexterity endowment facility faculty intelligence might potentiality qualification resourcefulness skill strength talent understanding awareness cognizance conversance familiarity fellowship intimacy relationship acuity acuteness astuteness brains brilliance cleverness cunning discernment discrimination farsightedness good taste guile ingenuity insight intellect intuition judgment keenness perception percipience perspicacity perspicuity refinement sagacity sensitivity sharpness shrewdness smartness smarts vision wisdom acceding accession accommodation accordance acknowledging adjustment affiliation affinity alliance amity approving arbitration arrangement assenting authorizing bargaining compatibility compliance complying compromise concert concession concordance concurring conformity congruity consistency correspondence endorsing granting mediation ratifying reconciliation similarity suitableness sympathy union unison verification verifying acknowledgment adjudication affidavit approval assent avowal bargain bond cartel charter codicil compact confirmation covenant indenture lease negotiation note oath okay piece of paper protocol recognition settlement stipulation the nod transaction treaty writ accordant agreeing amiable civil clubby concordant cordial courteous cozy empathic good-humored harmonious like-minded mellow neighborly pacific peaceable peaceful polite regular right nice sociable square shooting sympathetic ability acquaintance agreement amicable Understanding MRDs MRD Mr.D mrd test trial proving proof cogent conclusive detailed diagnostic discrete dissecting explanatory expository inquiring inquisitive interpretive investigative judicious logical organized penetrating perceptive perspicuous precise problem-solving questioning ratiocinative rational reasonable scientific searching solid sound studious subtle systematic testing thorough valid well-grounded dubious experimental flaky mostly working new pre-release suspect unready allegory analogizing analogy analyzing association balancing bringing together collating collation comparability connection contrast correlation discrimination distinguishing dividing estimation example exemplification identification illustration juxtaposition likeness likening measuring metaphor observation opposition paralleling ratio relating relation resemblance segregation separation similarity weighing challenge concours discussion game match meet meeting rencounter sport tournament trying balloon exploratory pilot preliminary probationary provisional tentative R and D analysis assay attempt audition check crack dry run effort endeavor essay examination experience experiment experimentation fling hassle investigation lick probation research and development shakedown shot showcase stab striving struggle test run trial and error trial run try try on tryout undertaking venture whack workout analytic beta comparison contest Testing CLL health Cancer bane blight blister boil corrosion corruption lesion rot scourge smutch sore ulcer affliction burden calamity cross disaster evil evil eye hydra jinx ordeal pestilence plague torment tribulation trouble vexation voodoo ache affection attack breakdown bug canker collapse complaint condition contagion contamination convulsions debility decrepitude defect disorder distemper endemic epidemic feebleness fever fit flu hemorrhage ill health illness indisposition infection infirmity inflammation malady misery pathosis seizure sickliness sickness spell stroke syndrome temperature unhealthiness unsoundness upset virus visitation cancroid excrescence fibrous tissue fibrousness fungus lump mole outgrowth parasite polyp swelling thickening wen ailment disability aggravation besetment blast bother botheration exasperation irritant nuisance pain pest problem thorn in side trial curse disease growth cancer
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