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Upfront Therapy for Myeloma; Impact on Choice at Relapse

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Shaji Kumar, MD, provides insight on the factors to consider when choosing a personalized approach to frontline therapy based on risk status and genetics in patients with multiple myeloma.


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square high-minded just outright reputable scrupulous trusty above-board law-abiding no lie on the up and up true blue treacherous unreasonable untruthful misleading fraudulent irresponsible unsuitable upfront Soft launch analysis cure healing medicine remedy therapeutics remedial treatment disease damage harm hurt injury behavior modification aversion therapy behavioral therapy conditioning counseling reinforcement retraining reward system therapy mindset attitude behaviorism ethos mental make-up mental processes mentality mind personality study psych psyche science of the mind way of thinking what makes someone tick where head is at physicality psychoanalysis psychology rehab care diet hospitalization medication operation prescription regimen rehabilitation surgery remedies antidotes assistance biologics correctives counteractants counteractions counteractives counteragents countermeasures countersteps cure-alls drugs elixirs fixes improvements medicaments medicants medicines panaceas pharmaceuticals pharmacons physics pills quick fixes redress reliefs restoratives supports therapies treatments pains stops diseases damages injuries Soft launch Therapy as long as because being considering inasmuch as now since whereas after concerning during notwithstanding pro supposing toward beneficial to conducive to for the sake of in contemplation of in exchange for in favor of in furtherance of in order to in order to get in place of in pursuance of in spite of in the direction of in the interest of in the name of on the part of on the side of to counterbalance to go to to the amount of to the extent of under the authority of with a view to with regard to with respect cause for for the reason that seeing that as a result of as things go by cause of by reason of by virtue of due to in as much as in behalf of in that in view of now that on the grounds that over owing to seeing thanks to through behind backing in agreement supporting all in all all things considered everything being equal forasmuch as in consideration of in light of insomuch as pending taking into account favor accept advocate appreciate approbate approve back be in favor of be on one's side buck for champion choose commend cotton to countenance encourage endorse esteem eulogize fancy flash on go for hold with honor incline lean toward look up to opt for patronize pick praise prize regard highly root for sanction single out support take a liking to take a shine to take to think well of tilt toward value disfavor hurt disrespect disagree discourage criticize neglect oppose thwart hinder deny hate dislike censure disallow dissuade protest disapprove reject refuse favoring accepting advocating appreciating approbating approving being in favor of being on one's side championing choosing commending countenancing encouraging endorsing esteeming eulogizing fancying forring going for holding with honoring inclining looking up to opting for patronizing picking praising prizing regarding highly sanctioning taking a liking to taking a shine to taking to thinking well of valuing disfavoring hurting disrespecting disagreeing discouraging criticizing neglecting opposing thwarting hindering denying hating disliking censuring disallowing dissuading protesting disapproving rejecting refusing Soft launch FOR For brunt shock bang blow bounce buffet bump clash concussion contact crash crunch crush encounter hit impingement jar jolt jounce kick knock meeting percussion pound punch quake quiver ram rap rock shake slap smash strike stroke thump tremble tremor wallop appulse smashup avoidance failure loss praise stillness impression influence repercussion meaning burden significance weight power mark imprint thrust consequences full force unimportance register collide crack up bang into smash up wrack up lose compliment aftermath after-effects causatum chain reaction end eventuality flak impact issue outcome payoff remainder residual residuum results upshot waves start origin cause source bash bat belt biff blindside bop clip clout clump collision crack cut ding jab knockout knuckle sandwich lick poke slam slug smack sock swat swing swipe thwack uppercut whack whomp zap luck good fortune flattery force pressure strain stress tension violence peace ease relaxation affray argument battle brawl break broil brush conflict confrontation difference of opinion discord discordance disharmony dispute donnybrook embroilment engagement fracas fray have a go at each other jam jump melee misunderstanding mix up opposition rift riot row rumpus run-in rupture scrap scrimmage set-to showdown skirmish harmony concord agreement compatibility truce calm clashes affrays arguments battles brawls breaks broils brushes bumps collisions concussions conflicts confrontations crashes difference of opinions discordances discords disharmonies disputes donnybrooks embroilments encounters engagements fracases have a go at each others impacts jams jars jolts jumps melees misunderstandings mix ups oppositions rifts riots rows rumpuses run-ins ruptures scraps scrimmages set-tos shocks showdowns skirmishes smashes wallops harmonies concords agreements compatibilities truces butt demolishment destruction dilapidation fender bender head-on pileup ruin sideswipe thud wreck construction creation building Soft launch Impact excellent preferred prime elect elite exclusive fine nice prize special valuable winner 24-karat A-1 exceptional exquisite first-class hand-picked popular precious preferential rare select solid gold top-drawer uncommon unusual bad common ordinary poor unimportant unrefined worst inferior sad option variety judgment decision favorite finding preference pick vote distinction alternative opportunity election cull extract evaluation discrimination verdict say discretion determination substitute weakness appraisal volition choosing cup of tea free will rating druthers rejection hate indecision admirable A-OK ace attractive best ever cat's pajamas choice commendable cool copacetic crackerjack deserving dream estimable good great greatest hunky dory keen laudable meritable meritorious neat out of sight out of this world peachy praiseworthy solid super super-duper superior unreal wicked wonderful worthy zero cool ugly shameful repulsive repugnant loathsome hateful detestable despicable contemptible imperfect unworthy adoption acceptance approbation appropriation approval assumption confirmation embracement embracing enactment endorsement espousal following maintenance ratification selection support taking on taking over taking up repudiation pass opposition disapproval refusal advantage aid ascendancy asset assistance authority avail blessing boon break comfort convenience dominance edge eminence expediency favor gain gratification help hold improvement influence interest lead leeway leg-up leverage luck mastery odds position power pre-eminence precedence prestige prevalence profit protection recognition resources return sanction starting superiority supremacy upper hand utility wealth handicap bad fortune stop waste subservience block impotence restriction obstacle drawback misfortune bad luck obstruction hindrance blockage disadvantage disfavor injury hurt harm loss inferiority incapacity advantages aids assets authorities blessings boons breaks choices comforts conveniences edges eminences expediencies favors gains goods gratifications helps holds improvements influences interests leads leg-ups positions powers preferences profits protections recognitions returns sanctions startings superiorities supports upper hands utilities handicaps bad fortunes stops wastes blocks restrictions obstacles drawbacks misfortunes bad lucks obstructions hindrances blockages disadvantages injuries losses weaknesses incapacities appointment allotment assigning authorization certification commissioning delegation deputation designation empowering installation naming nomination ordination promotion appointments allotments approvals assignings authorizations certifications choosings commissionings delegations deputations designations elections empowerings installations namings nominations ordinations promotions selections rejections refusals Choice Soft launch recidivism recurrence regression worsening backsliding fall lapse loss repetition retrogression return reversion setback fall from grace turn for the worse achievement success healing progress strengthening fall back degenerate retrogress worsen revert sicken sink fade regress fail suffer backslide recidivate be overcome be overtaken slide back slip back turn back get better win reach fight strengthen rise help develop heal grow increase improve attack access ailment bout breakdown convulsion disease failure fit illness paroxysm relapse seizure spasm spell stroke throe support retreat flight defense submission reprisal sustenance surrender shield shelter resistance protection aid health attacks abuses aggressions belligerence blame calumnies censures combativenesses criticisms denigration denunciations impugnments libels pugnacity slanders vilifications supports retreats flights defenses approvals submissions reprisals surrenders shields shelters resistances protections aids commendations compliments praise backset disappointment discouragement downfall meltdown reversal reverse apostatize deviate sin slip decline abate cheapen decay decrease depreciate deteriorate diminish disimprove disintegrate droop drop dwindle ebb fall off flag go downhill go to pot go to the dogs hit the skids languish lose value lower pine recede retrograde rot sag settle shrink slide subside wane weaken go up say yes accept flourish build advance extend expand raise enhance ascend enlarge laud compliment abatement comedown cropper decrepitude degeneracy degeneration descent deterioration devolution diminution dissolution dive downgrade downturn dwindling ebbing enfeeblement failing flop on the skids pratfall recession senility slump waning weakening strength growth development upgrade ascent betterment improvement accomplishment Soft launch Relapse corruption disease malignancy sickness tumor canker carcinoma big C long illness health wholesomeness benignity Cancer Soft launch cancer oncology Soft launch
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