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Upfront Use of Immunotherapy for NCSLC

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Panelists Mark Socinski, MD; Tracey Evans, MD; Alexander Drilon, MD; Vali Papadimitrakopoulou, MD; and Jared Weiss, MD, remark on the FDA approval of upfront pembrolizumab in non–small cell lung cancer and discuss data regarding the use of pembrolizumab in combination with chemotherapy.


cancer oncology easy genuine instinctive real simple frank innocent plain primitive provincial rustic artless being oneself candid childlike credulous direct folksy forthright homey ignorant impulsive inartificial ingenuous laid-back naive simplehearted sincere spontaneous straightforward trusting unassumed uncontrived undesigning unembarrassed unfeigned unforced unlabored unpolished unpretentious unschooled unsophisticated unstudied unworldly up-front complex complicated difficult dishonest false intricate cultured metropolitan modern sophisticated abnormal affected artificial different fixed modified pretended refined uncommon unnatural natural fair impartial free transparent receptive objective mellow disinterested guileless on the level open-and-shut openhearted unbiased uncommitted unconcealed unprejudiced unreserved lay it on the line undisguised undissembled sure definite decided certain obstructed blocked shut closed tricky dark prejudiced partial subjective shifty lying deceptive vague unclear deceitful ambiguous unavailable inaccessible locked fastened cloudy unjust unfair biased open heartfelt outspoken trustworthy earnest serious aboveboard actual bona fide dear devout faithful no-nonsense regular righteous saintly square true-blue unaffected wholehearted true dead-level honest to God like it is meant no fooling on the line on up and up pretensionless sure enough twenty-four carat devious invalid unimportant trivial flippant untrustworthy insincere unreal counterfeit accurate authentic authoritative convincing credible dependable ethical exact honest honorable kosher levelheaded mature plausible realistic responsible secure sensible solid steadfast straight tried tried-and-true truthful unfailing upright valid veracious principled always there rock solid there to be trusted trustable corrupt unreliable undependable unbelievable trustworthy\u002Ftrusty in advance indirect coy up front virtuous decent equitable conscientious proper reliable fair and square high-minded just outright reputable scrupulous trusty above-board law-abiding no lie on the up and up true blue treacherous unreasonable untruthful misleading fraudulent irresponsible unsuitable upfront adoption benefit handling help need operation practice purpose service treatment usage value account advantage appliance applicability appropriateness avail call capitalization cause convenience custom end exercise exercising exertion fitness good habit helpfulness mileage mobilization necessity object occasion point profit reason relevance serviceability usability usefulness utility way wont worth wear and tear disadvantage harm hindrance hurt injury inappropriateness loss unsuitability uselessness handle control adopt run work wield utilize accept employ exploit manage apply operate spend manipulate exhaust expend regulate exert relate ply bestow govern waste capitalize bring into play bring to bear draw on run through take advantage of avail oneself of do with find a use make do with make the most of make use play on press into service put forth put into action put to use put to work set in motion turn to account save leave alone stop halt let go neglect mismanage abstain repudiate reject cease renounce misuse abuse do an injustice to impose on use wrong commend approve esteem care for defend treasure honor praise compliment adulate acclaim revere prize respect protect preserve cherish abused abusing adapt affiliate affirm appropriate assent assume borrow embrace endorse espouse follow go down the line go in for imitate maintain mimic opt ratify seize select support take on take over take up tap repulse return give oppose disagree disown shun disallow discard disapprove refuse release deny adopted aid asset assistance benediction betterment blessing boon cream extras favor gain godsend gravy interest perk prosperity welfare handicap bad fortune misfortune bad luck disapproval obstruction blockage U.S.E steezy hypnotherapy chemotherapy chemo therapy misanthropy domino theory in theory in the raw in there am on the up in the rear taking the rap is on the up am on the air as long as because being considering inasmuch as now since whereas after concerning during notwithstanding pro supposing toward beneficial to conducive to for the sake of in contemplation of in exchange for in favor of in furtherance of in order to in order to get in place of in pursuance of in spite of in the direction of in the interest of in the name of on the part of on the side of to counterbalance to go to to the amount of to the extent of under the authority of with a view to with regard to with respect cause for for the reason that seeing that as a result of as things go by cause of by reason of by virtue of due to in as much as in behalf of in that in view of now that on the grounds that over owing to seeing thanks to through behind backing in agreement supporting all in all all things considered everything being equal forasmuch as in consideration of in light of insomuch as pending taking into account favor accept advocate appreciate approbate approve back be in favor of buck for champion choose commend cotton to countenance encourage endorse esteem eulogize fancy flash on go for hold with honor incline lean toward look up to opt for patronize pick praise prize regard highly root for sanction single out support take a liking to take a shine to take to think well of tilt toward value disfavor hurt disrespect disagree discourage criticize neglect oppose thwart hinder deny hate dislike censure disallow dissuade protest disapprove reject refuse favoring steezy FOR goes loco boxlike czarlike knocks back waxlike negligee goes like wax like like silk makes like looks like shakes leg takes leak takes look corruption disease malignancy sickness tumor canker carcinoma big C long illness health wholesomeness benignity cancer steezy Cancer ontology unclog ecology un clog analogy unclogs un clogs oncology
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