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What is CRISPR?

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In this video Paul Andersen explains how the CRISPR/Cas immune system was identified in bacteria and how the CRISPR/Cas9 system was developed to edit ...

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educational videos science videos high school science CRISPR CRISPER Cas9 Gene editing Molecular biology Bacteriophage Clustered Regularly-Interspace Simple Palinomic Repeats Repeats SpacerDNA crRNA trcrRNA chimera gRNA Student students student uni study university stdent learning teacher college party procrastinate sleep pupils pupil school teachers slob bum alcohol lazy hangover search final trial check essay lick exam fling ordeal try tryout oral proof comp conclusion assess prove verify confirm question analyze inquire validate assay try on match up stack up try out disprove breakdown dissection dissolution division inquiry investigation partition reasoning resolution scrutiny separation study subdivision test beat a dead horse chew over confab consider estimate evaluate figure figure out get down to brass tacks hash inspect interpret investigate judge kick around rehash resolve scrutinize sort out spell out talk game think through appraisal assessment estimation evaluation examination inspection measurement rating survey valuation appraise apprise check out examine eyeball measure peg rate read see size size up valuate value weigh claiming confrontation dare defiance demanding demur interrogation objection protest provocation remonstrance summons to contest threat ultimatum accost arouse ask for assert beard brave call for call out claim confront cross defy demand denounce exact face down face off face the music fly in the face of hang in impeach impose impugn insist upon invite competition make a point of make a stand object to provoke query reclaim require search out stand up to stick it out stimulate summon tax throw down the gauntlet vindicate analysis challenge TEST trying re-search testing juice steroids roids roider testosterone explode exploding explodeable explodarasticleibeaver beaver eddie fail failed pass passed failed the test passed the test testiment testimonial judgement set up torque testing academic cultural scholarly didactic tutorial educational educative enlightening explanatory helpful illuminating informational instructional useful advancing developmental enriching expanding improving refining learned lettered literary pedantic edifying intellectual illuminative inspiring instructive uplifting broadening scholastic civilizing canned taped book can catalog chalk up chronicle copy cut cut a track document dub enroll enter enumerate file indite inscribe insert jot down keep account lay down list log make a recording mark mark down matriculate note post preserve put down put in writing put on file put on paper put on tape register report set down tabulate take down tape tape-record transcribe video videotape wax write in audiotape make a tape TV set audio baby-sitter boob tube box eye idiot box receiver small screen station telly tube vid television set record television art system skill lore branch wisdom ignorance disorder ability accomplishment address aestheticism capacity civilization class courtesy cultivation delicacy dignity discrimination dress elegance elevation enlightenment erudition experience fashion finish gentility good taste grace improvement kindness learning manners nobility perception polish politeness practice proficiency refinement savoir-faire science tact training urbanity apprenticeship background book learning brainwashing breeding catechism coaching culture direction discipline drilling edification guidance inculcation indoctrination information learnedness literacy nurture pedagogy preparation propagandism proselytism reading rearing scholarship schooling study teaching tuition tutelage tutoring bookishness brains intellectuality knowledge letters pedantry savvy scholarliness studiousness advice ammo break chapter and verse clue confidence counsel cue data dirt dope dossier earful illumination info inside story instruction intelligence leak lowdown material message network notice notification orientation propaganda report scoop score tidings tip what's what whole story word accomplishments acquaintance apprehension attainments awareness cognition comprehension consciousness discernment doctrine dogma education expertise facts familiarity goods grasp insight judgment know-how light observation philosophy picture power principles recognition substance theory acquirements literature research SCIENCE! Science huge great big long large steep lofty giant flying aerial grand alpine teeny tiny lowly upset little minute small short humble ground low mean down sober soft weak stiff unusual rich sharp strong dear special costly lavish stupid poor calm normal bland mild cheap common serious noble leading chief ruling capital arch grave extreme crucial eminent exalted minor elated excited joyful merry psyched pumped bouncy drunk stoned tipsy doped potted tanked treble acute piping rank loud putrid rancid smelly aloft atop beyond high on high on top of over overhead raised superior upon elevated high-reaching in the clouds montane mountainous rangy snowcapped soaring towering assertive audacious bold brazen certain cocksure collected complacent composed confident cool gung ho gutsy imperturbable overconfident poised positive puffed up pumped up pushy rosy sanguine secure self-assured self-confident self-possessed sure unflappable unhesitating upbeat awkward beefy colossal cumbersome cumbrous enormous gross heavy hefty hulking immense mammoth massive ponderous substantial unhandy unmanageable unwieldy voluminous weighty airy animated blithe bright bucked buoyant cheery chipper chirpy contented effervescent enlivening enthusiastic full of pep gay glad gladsome good-humored good-natured hearty hilarious hopeful in good spirits in high spirits jaunty jocund jolly lighthearted lively optimistic peppy perky pleasant roseate snappy sparkling sprightly sunny sunny side up vivacious winsome zappy zingy zippy bet on brave convinced counting on courageous dauntless depending on expectant expecting fearless having faith in intrepid presuming presumptuous racked satisfied self-reliant self-sufficient trusting unafraid undaunted uppity valiant above assured bulky cheerful academy hall jail faculty college group class party set sect clique circle pupils faith outlook belief stamp creed way disbelief tutor coach lead show prime manage direct inform train verse drill guide ignore hide learn forget academe academic community academicians savants school breed cultivate develop discipline educate feed form foster nourish nurture provide for rear support teach Mafia assembly bunch cabal camarilla camp clan club companions company comrades coterie crew cronies crowd crush fraternity gang in-group insiders intimates lot mob outfit posse ring society sorority branch brand cast caste character classification collection color degree denomination department description designation distinction division domain estate family feather frame genre genus grade grain grouping hierarchy humor ilk kidney league make mold name nature order origin property province quality range rank rate section selection source species sphere standing status stripe style suit temperament value variety break in cram hone lay it out for lick into shape prepare pull one's coat put through the grind put through the mill ready abbey cloister monastery religious community retreat academia bring up convent School data census stats demographics demography enumeration poll population tally statistics abstracts brass tacks chapter and verse circumstances compilations conclusions details documents dope dossier evidence experiments facts figures goods info input knowledge materials measurements memorandums notes picture proof reports results scoop score testimony whole story account agenda archive arrangement ballot bill brief bulletin calendar canon catalog catalogue checklist contents dictionary directory docket draft file gazette index inventory invoice lexicon lineup listing loop manifest memorandum menu outline panel program prospectus register roll roll call row schedule screed scroll series slate syllabus table tally thesaurus ticket timetable vocabulary appendix chart compendium digest graph illustration list plan record summary synopsis table of contents tabulation accomplishment achievement credentials history performance performance history track track record Statistics salient striking notable marked eminent famous peculiar renowned vague obscure common alarm cue sign omen nod flare token alert wink flag okay mark bleep SOS veto warn wave flash Mayday bell blast buzzer call caution clock cry drum flap forewarning gong high sign horn scramble scream shout signal siren squeal tip tip off tocsin trumpet warning whistle yell admonition forewarn give the high sign inform notify put on guard wave flag augur forebode forecast forerun foreshow foretell harbinger herald indicate portend predict presage signify bell sound breedle computer sound ding eep feep tone beacon drift float guide marker announce beep buoy Signal also moreover additionally again along along with and as well as well as besides conjointly further furthermore in conjunction with in like manner including likewise more more than that on top of over and above plus still to boot together with too withal added aggrandized amassed another augmented bounteous deeper else enhanced exceeding expanded extended extra farther fresh heavier higher in addition increased innumerable larger major massed new numerous other spare supplementary too many wider And? AND cry roar crash buzz clamor blast bellow shot blare racket ring thud row babel hubbub boom squawk fuss babble bedlam clang peal hoo-ha fracas jangle din yelp tumult bang uproar outcry talk calm quiet peace order echo noise sound sound properties sound transmission chaos commotion confusion disquiet disquietude furor madhouse maelstrom pandemonium shambles turmoil agitation brouhaha bustle clinker complaint convulsion discord exclamation ferment hassle hubba-hubba hullabaloo hurly-burly lament protesting remonstrance ruckus shout shouting to-do upheaval vociferation bluster bump clank clash hurtle rattle shatter smash bash belt blow buffet burst clap clip clout cuff explosion pop report slam slap smack snap splintering splitting stab stroke thump thwack wallop whack wham clothesline comment gossip grapevine leak mere talk rumble rumor scandal scuttlebutt talk of the town word of mouth acoustics clatter crack hearsay Noise unreal void barren bad absent vain worthy filled valid full good true abortive anticlimactic bootless defeasible feckless feeble forceless fruitless futile idle impotent inadequate incompetent indecisive inefficacious inefficient inept inferior innocuous inoperative invertebrate lame limited neutralized nugatory null null and void paltry powerless spineless unable unavailing unfruitful unproductive unprofitable unsuccessful withered worthless baseless fallacious false ill-founded illogical irrational mad not binding not working reasonless sophistic unreasonable unreasoned unscientific unsound untrue wrong airy blank chimerical dead defunct departed dreamlike dreamy empty ethereal extinct extinguished fancied few and far between flimsy gone gossamery groundless hallucinatory hypothetical illusory imaginary imagined immaterial imponderable insubstantial legendary lost missing mythical negative passed away passed on perished shadowy tenuous ungrounded unsubstantial vacant vague vaporous without foundation beside the point casual frivolous frothy inconsequential inconsiderable indifferent insignificant irrelevant little low-ranking meaningless minor minute negligible nonessential nothing of no account of no consequence petty picayune second-rate shoestring slight trifling trivial unnecessary useless zero zilch zip avoided ineffective ineffectual invalid negated not viable set aside sterile unconfirmed unenforceable unratified unsanctioned voided emasculate no go no way not effective slack-spined unavailable nonexistent unimportant NULL Null thesis guess theorem premise axiom ground layout basis system scheme belief reason plan data proposal term surmise position lemma fact proof truth acceptance accepting assuming conjecture expectation fancy hunch hypothesis inference posit postulate postulation presumption presupposition shot shot in the dark sneaking suspicion stab supposal supposition suspicion theorization theory admission assent assumption assurance avowal certainty conclusion confidence conviction credence credit deduction divination faith feeling hope idea impression intuition judgment knowledge mind mindset notion opinion persuasion profession reliance thinking trust understanding view concept credo creed doctrine dogma fundamental gospel gospel truth ideology law precept principle say-so tenet abstraction apprehension approach big idea brain wave brainchild conceit conception conceptualization consideration fool notion image intellection perception slant thought twist wrinkle guesstimate guesswork perhaps stab in the dark theorizing advancement affirmation allegation assertion asseveration charge claim contestation declaration demurrer deposition discussion explanation hurrah maintaining plea predication rumpus stand contention Hypothesis William william will.i.am Sealy sealy Gosset Ap biology AP Biology division medicine analysis diagnosis inquiry cytology genetics etiology zoology histology connection ecology botany bioscience physics chemistry biology dissection embryology examination investigation morphology physiology animal biology anthropology biological science environmental science natural science science of life study of living things life sciences pure science science of matter anatomy life science Biology bio science life class freshman year school dulaney evolution learning college garbage pointless idiotic annoying bitch teacher boring education teaching scholar pupil junior graduate observer learner novice skill docent disciple grad teacher academician lecturer professor scholastic student tutor amateur beginner flunky greenhorn heel neophyte new kid on block newcomer novitiate probationer rook rookie starter tenderfoot tyro abecedarian apprentice buckwheater catechumen colt fish fledgling greenie initiate new kid on the block new person recruit trainee adherent apostle attendant booster buff bug cohort convert devotee enthusiast fan fanatic fiend freak groupie hound junkie nut partisan proselyte rooter satellite sectary sectator supporter votary witness zealot bookworm cub first of May gremlin know from nothing mark plebe postulant prentice punk academic Student students uni study university stdent learning college party procrastinate sleep pupils school teachers slob bum alcohol lazy hangover lecturer scholar tutor coach educator trainer adviser pundit mentor teach guide pupil Dutch uncle aide attorney authority backseat driver buttinski clubhouse lawyer confidant consultant counsel counselor director doctor expert friend helper instructor judge kibitzer lawyer monitor partner priest quarterback referee righthand person second-guesser teacher drill instructor skipper advocate ambulance chaser front legal beagle legal eagle lip mouthpiece pleader solicitor squeal authoritarian bully despot drill sergeant enforcer formalist master sergeant stickler strict teacher sundowner tyrant attendant captain chaperon cicerone conductor controller convoy criterion design docent escort example exemplar exhibitor genie genius guiding spirit guru ideal inspiration lead leader lodestar model paradigm pathfinder pattern pilot pioneer rudder scout standard superintendent usher vanguard disciplinarian Teachers Teacher mind idea theory notion view say-so thesis guess eye take slant fancy think thing fact proof truth admonition advisement advocacy aid bum steer caution charge consultation counsel directions dissuasion encouragement exhortation forewarning guidance help information injunction input instruction judgment lesson news opinion persuasion prescription proposal proposition recommendation steer suggestion teaching telltale tidings tip tip-off two cents' worth warning word word to the wise estimation evaluation finding interpretation outline reasoning report study summary appraisement assessment estimate pricing rating reckoning stock survey valuation air angle approach belief bent bias character demeanor disposition frame of mind headset inclination leaning like it is mental state mindset mindtrip mood perspective philosophy point of view position posture predilection prejudice proclivity reaction routine say so sensibility sentiment set stance stand standing standpoint temper temperament twist where one is at acceptance admission assent assumption assurance avowal axiom certainty conclusion confidence conjecture conviction credence credit deduction divination expectation faith feeling hope hypothesis impression intuition knowledge postulation presumption presupposition profession reliance supposition surmise suspicion theorem thinking trust understanding concept credo creed doctrine dogma fundamental gospel gospel truth ideology law postulate precept principle tenet advice analysis appraisal attitude opinions Opinion academic cultural scholarly didactic tutorial educational educative enlightening explanatory helpful illuminating informational instructional useful advancing developmental enriching expanding improving refining learned lettered literary pedantic edifying intellectual illuminative inspiring instructive uplifting broadening scholastic civilizing machinery mechanics automation computers robotics hi tech high tech technology Technology needed fulfilled satisfied abandoned renounced loved valued capital cardinal chief constitutive crucial foremost fundamental imperative indispensable leading main necessary necessitous needful prerequisite principal required requisite right-hand wanted avoiding brief criminal elusive ephemeral errant erratic escaping evading evanescent fleeting flitting flying fugacious hot impermanent lamster momentary moving on the lam passing planetary running away short short-lived temporary transitory unstable volatile wandering bankable commercial fit for sale good merchandisable merchantable profitable salable sellable selling sought after sound trafficable vendible all-important basic binding bottom-line compelling compulsory de rigueur decisive elementary exigent expedient incumbent on mandatory momentous name of game obligatory paramount pressing prime quintessential significant specified unavoidable urgent vital blatant dishonorable disreputable flagrant glaring ill-famed infamous noted obvious opprobrious overt patent popular prominent questionable scandalous shady shameful unadmirable one belled undisputed well-known wicked burning called-for clamant clamorous critical crying demanded demanding driving essential heavy hurry-up immediate impelling important importunate insistent instant life and death persuasive primary salient serious top-priority touch and go touchy weighty fugitive marketable notorious WaNtEd wänted What?! what what? crispr crispr fresh plump firm short green ripe limp soft warm long brisk clear bracing dull brief biting tart abrupt pithy terse vague kind fuzzy nice sweet neat spruce tidy untidy bitter bleak blighting cold crisp cutting freezing harsh nipping penetrating raw animating chilly cool energizing exhilarative fortifying invigorating lively quickening refreshing restorative reviving rousing stimulating stimulative tonic vigorous brittle crispy crumbly delicate flimsy fracturable fragile frail frangible friable shatterable shattery splintery vitreous weak bluff blunt boiled down breviloquent brusque compendiary compendious concise curt hasty laconic limited little sharp short and sweet skimpy small snippy succinct surly to the point exhilarating keen nippy snappy breakable crumbling inelastic shivery Crisper RNA chromosome gene genetic code heredity nucleic acid DNA Gene genes amazing gods gift ladies man huge wang great nice religious travel singer penis male human gay wonder guy name texas art cool insane scooter crazy gangsta butt head mean cute manly tall censor choose adapt select alter revise delete trim rehash excise polish check style cut doctor emend draft finish scrub report assign set up redact ruin worsen spoil keep alteration amelioration amending amendment changing editing emendation improvement indemnification mending modification rectification redress reexamination remodeling repair reparation rereading revisal revising righting afterlight correction homework overhauling recension reconsideration rectifying redaction redraft reediting rescript restyling retrospect retrospection review updating change abridge black out blacklist bleach bleep blue-pencil bowdlerize clean up conceal control cork criticize decontaminate drop the iron curtain edit examine expurgate exscind inspect launder narrow oversee prevent publication purge purify put the lid on refuse transmission repress restrain restrict revile sanitize scissor out squelch sterilize strike out supervise communications suppress withhold amass anthologize arrange assemble bring together collate collect colligate collocate compose concentrate congregate consolidate cull draw together garner gather get together glean group heap up marshal muster organize put together recapitulate unite abbreviate blue pencil boil down chop coagulate compact compress constrict contract curtail cut down decoct densen digest encapsulate epitomize inventory precipitate press together précis put in a nutshell reduce shorten shrink snip solidify sum summarize summate synopsize telescope thicken revision compile condense Editing molecular biology atomic little minute bottom entry-level feeblest fewest finical first gutter infinitesimal last lowest meanest microcosmic microscopic minimal minimum minutest molecular most trivial nadir next to nothing niggling piddling poorest second short-end third tiniest trivial unimportant diminutive exact exiguous fine inconsiderable insignificant invisible microbic miniature minim minuscule peewee precise puny slender teeny-weeny tiny wee least Molecular flock gather bundle parcel package collect bunch scatter spread divide let go amassed assorted blended clustered heterogeneous indiscriminate massed melded miscellaneous mixed motley multifarious promiscuous varied variegated banded bent braided bunched clinched clumped coiled engaged entangled fastened gnarled hitched intertwined knotty lashed lassoed linked looped meshed perplexed seized snagged snarled spliced tangled twisted warped whirled assemble cluster congregate cram crowd group herd huddle mass pack aggregate amass array compile congress convene converge convoke corral flock together get hold of heap hoard muster rally rendezvous round up save scare up stockpile accumulate agglomerate center centralize coalesce combine compact compress congest conglomerate consolidate constrict contract cramp draw together eliminate embody focalize focus forgather garner get to the meat heap up integrate intensify localize narrow pile reduce salt away store strengthen swarm unify zero in bear chock crush deluge elbow jam jam-pack justle overcrowd pack 'em in pack like sardines push ram sardine shove squash squeeze squish stream surge swamp throng top off troop knotted concentrate plain smooth quiet clean snap light picnic cinch walkover facile lucid mild no sweat unclear vague jumbled ornate mature older aware hard complex smart pure classic modest vanilla mere rustic single spartan austere folksy homely homey humble lowly sheer unfussy unmixed impure immodest unchaste abnormal abstruse exacting dirty polluted honest natural direct basic amateur frank square green artless bald naive naked sincere stark uncommon devious stupid silly fat thick dense dull dumb feeble inane obtuse slow soft slight thin complete consummate downright entire flat out free full infinite no catch no fine print no holds barred no ifs ands or buts no joke no strings attached outright plenary simple straight out supreme thorough total unabridged unadulterated unconditional unlimited unqualified unrestricted utter bare bare-bones bleak dour primitive severe spare subdued unadorned unembellished blunt chaste cold essential literal meager scant unornamented casual nonchalant unstudied celibate continent controlled decent decorous elegant immaculate impotent inexperienced innocent intemerate monogamous moral neat platonic proper prudish refined restrained spotless stainless unaffected unblemished uncontaminated undefiled unstained unsullied unwed vestal virginal virtuous wholesome childish credulous guileless immature ingenuous spontaneous trustful trusting unfeigned absolute careless childlike Simples Simple echo replay rerun original recite rehash renew restate imitate relate iterate chime redo recur reform rehearse return quote revolve din ditto revert reappear rework reoccur reissue reprise recast retell remake resay reshow run over stop assert asseverate attest aver avouch avow certify cinch clinch confirm cross heart declare guarantee have a lock on ice insist lock up maintain nail down okay predicate profess pronounce put on ice ratify repeat rubber-stamp say so set state swear swear on bible swear up and down testify vouch witness beat a dead horse go on about hammer home overwork pound discharge disgorge emit eruct eructate erupt give off gush hiccup irrupt ventilate vomit adduce advance allege allude to appeal to enumerate evidence excerpt exemplify extract get down to brass tacks give as example illustrate with indicate instance lay mention name number offer point out present recount refer to reference remember reminisce specify spell out tell copy duplicate replicate reproduce Photostat Xerox carbon cartoon clone counterfeit delineate depict draw dupe engrave engross fake forge knock off limn manifold mimeo mirror mold paint paraphrase photocopy picture plagiarize portray reduplicate reflect represent rewrite sculpture simulate sketch stat trace transcribe affirm belabor belch cite Repeat rainbow monster fancy figment mirage snare bubble specter bogy truth fact bogeyman bump in the night chimera delusion hallucination haunt illusion phantasm phantom revenant spirit spook visitant castle in the air daydream fantasy head trip idea image imagination impression incubus mental picture nightmare pie in the sky pipe dream reverie speculation thought trance vagary wraith big eyes conception envisagement envisioning eyes for fabrication fondness hankering imaginativeness inclination invention itch notion partiality penchant picture predilection preference relish romancing sweet tooth vision yearning yen Atlantis air castle apparition appearance conceiving creativity externalizing fairyland fancying fantasia flight flight of imagination fool's paradise imagining mind trip objectifying originality trip utopia dream fable falsehood fiction improvisation lie production aberration abortion anomaly curiosity geek grotesque malformation miscreation misshape monstrosity mutant mutation oddity queer rarity sport weirdo freak
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